SPRINGER TUMOR METABOLOME TARGETING AND DRUG DEVELOPMENT 2014 RETAIL EBOOK-kE
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Torrent File Content (3 files)
SPRINGER.TUMOR.METABOLOME.TARGETING.AND.DRUG.DEVELOPMENT.2014.RETAIL.EBOOK-kE
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Description
TITLE: TUMOR METABOLOME TARGETING AND DRUG DEVELOPMENT
PUBLISHER: SPRINGER LANGUAGE: ENGLISH
LINK: http://is.gd/IXjwjU RELEASE TYPE: RETAIL
FORMAT: PDF RELEASE DATE: 2014.03.09
ISBN: 9781461495451 STORE DATE: 2014
SAVED.MONEY: 119 EURO DISKCOUNT: 01 x 05MB
AUTHOR: KANNER, STEVEN (ED.)
BOOK
In this volume, the major metabolic alterations identified in
cancer and tumor-associated cells are explored, including
discussions of former and emerging approaches to drug development
in targeting cancer cell metabolism
The metabolic network in cells promotes the generation of both
energy and biomass needed for them to grow, divide and
differentiate. However, the metabolism of malignant cells
generally varies from that of normal cells. These differences
provide a platform for the discovery of new approaches to
targeting potential vulnerabilities in cancer cells for
therapeutic options Some of the significant changes that occur
involve ATP production and consumption that modulates the ATP to
ADP ratio, hypoxia and the effects of reactive oxygen species on
glycolysis, regulation of mitochondrial respiration, induction
and suppression of autophagy, and the Warburg effect and
"reverse" Warburg effect--these topics and more are discussed in
this volume
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